AstraZeneca Bioinformatics Scientist Job Opening – Apply Online
Senior Scientist Bioinformatics
Locations: India – Bangalore
Time Type: Full-time
Posted On: Posted Yesterday
Time Left to Apply: End Date: April 30, 2025 (27 days left to apply)
Job Requisition ID: R-222219
Introduction to Role:
The Senior Scientist will apply scientific domain-specific knowledge (in bioinformatics) and/or clinical disease area expertise, specialized data processing techniques, analytical and machine learning capabilities to extract scientific insight and hypotheses from data. The role will work in partnership with scientists and clinicians to support the generation of innovative solutions, within defined project scope and aligned to established frameworks, which support decision-making in pre-clinical, development, and post-market activities.
Job Title: Senior Scientist Bioinformatics
Career Level: D
Introduction to Role:
Join AstraZeneca, a pioneering biopharmaceutical company that’s not afraid to do things differently. We’re seeking a highly skilled Bioinformatics researcher with a strong desire to enable multi-omics biology in drug discovery and development. You’ll be part of our Predictive AI & Data department within the Clinical Pharmacology and Safety Sciences (CPSS) function. This is a unique opportunity to work with industry leaders, contribute to the development of future drugs across many diseases, and grow beyond what you thought possible.
Accountabilities:
● Build predictive AI capabilities that utilize multi-omics technologies to measure transcripts or genome variants and discover novel mechanisms of action for compounds and therapies.
● Drive hypothesis generation by applying computational biology approaches, data integration, and biological knowledge.
● Implement new predictive capabilities using computational biology to translate omics data into biological insights.
● Collaborate with academic research groups and contribute to publications in peer-reviewed journals.
● Educate and train AstraZeneca colleagues in omics data interpretation and related areas.
● Coordinate and liaise with external suppliers of bioinformatics capabilities to deliver on urgent projects and develop capabilities.
Essential Skills/Experience:
● PhD in computational (bio)sciences (e.g., computational biology, bioinformatics, genomics, transcriptomics, or computer science) is preferred; or MSc (or equivalent) with experience in independent research in high-throughput omics data will also be considered.
● Demonstrated experience in ML or DL algorithms and predictive modeling applied to biological or biomedical problems.
● Demonstrated experience in genomics or transcriptomics data analysis. Skill sets in additional computational biology domains are a plus.
● Good applied knowledge of statistics (e.g., parametric and non-parametric tests, p-values, correlation metrics, PCA) and good experimental design practices (e.g., batch effects, confounding factors).
● Demonstrated expertise in R and Python.
● Team player mindset and ability to explain complex topics to scientists from other disciplines.
● Ability to communicate effectively (written and spoken) in English.
● Experience in independent scientific research.
● Knowledge of molecular mechanisms of disease or human biomedicine, particularly in a drug safety context.
● Excellent ability to work on multiple projects at the same time.
● Knowledge of drug discovery or pharmaceutical development.
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