Zydus Group Scientist Jobs – MSc & PhD Biotech, Biochem Apply Online
Vaccine Formulation Scientist
Ahmedabad, Gujarat, India
About the job
Job Overview:
We are seeking a highly skilled and motivated Vaccine Formulation Scientist to join our innovative R&D team. The role involves designing and optimizing vaccine formulations, focusing on stability, immunogenicity, and scalability for various delivery platforms. The ideal candidate will have experience with adjuvants, emulsions, and nanoparticle systems, along with an understanding of regulatory and manufacturing requirements for vaccine production.
Key Responsibilities:
- Design and develop vaccine formulations, including adjuvants, emulsions, nanoparticles, and combination products, with a focus on immune response enhancement and long-term stability.
- Conduct pre-formulation studies to evaluate the physicochemical properties of antigens, excipients, and adjuvants.
- Optimize formulations for immunogenicity, delivery, and scale-up, using advanced technologies such as emulsions, liposomes, and particulate systems.
- Perform stability testing at various conditions (e.g., temperature, humidity) and analyse data to ensure product shelf-life and safety.
- Collaborate with cross-functional teams, including process development, analytical, and regulatory departments, to ensure smooth transition from R&D to clinical manufacturing.
- Develop and implement robust manufacturing processes for scalable vaccine formulation production.
- Stay current on advancements in vaccine adjuvant technologies, delivery systems, and regulatory requirements.
- Prepare detailed technical reports, SOPs, and documentation for regulatory submissions.
- Support tech transfer activities for moving formulations from the lab to large-scale production.
Qualifications:
- PhD or Master’s in Pharmaceutical Sciences, Biochemistry, Biotechnology, or related field with a focus on vaccine development or formulation science.
- 5-10 years of hands-on experience in vaccine formulation development.
- Strong expertise in adjuvant systems (e.g., alum, squalene-based emulsions, saponins) and immune modulation strategies.
- Experience in formulation stability studies and data analysis.
- Familiarity with cGMP, GLP, and regulatory guidelines related to vaccine development.
- Excellent problem-solving, communication, and teamwork skills.
Preferred Skills:
- Knowledge of sterile formulation and lyophilization techniques.
- Hands-on experience with characterization techniques (e.g., particle sizing, zeta potential, HPLC, DLS).
- Familiarity with immunological assays (e.g., ELISA, flow cytometry) for evaluating vaccine efficacy.
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