Associate Scientist – Downstream Process Development
Syngene is an innovation-led contract research, development, and manufacturing organization offering integrated scientific services from early discovery to commercial supply. We are currently seeking an experienced Associate Scientist – Downstream Process Development to join our team in Bangalore. As an organization, we prioritize safety in all aspects of our work and strive to create a culture of environmental, health, and safety (EHS) awareness and compliance.
About Syngene
Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit.
Mandatory expectations for all roles as per Syngene safety guidelines:
- Overall adherence to safe practices and procedures
- Contributing to the development of procedures, practices, and systems for safe operations
- Driving a corporate culture that promotes environment, health, and safety (EHS) mindset
- Ensuring safety of self, teams, and lab/plant by adhering to safety protocols and EHS requirements
- Completing all assigned mandatory trainings related to data integrity, health, and safety measures on time
- Compliance to Syngene’s quality standards
- Holding self and their teams accountable for safety goals achievement
- Governing and reviewing safety metrics periodically
Job Purpose
The Associate Scientist – Downstream Process Development will be responsible for designing and executing experiments to develop scalable purification processes. They should have a strong understanding of protein chemistry, preparative chromatography, and/or membrane separation techniques for manufacturing biologics. The individual will also contribute to general lab maintenance, inventory management, and analytical assays as required.
Key Responsibilities
- Support designing and execution of experiments for process development
- Draft experimental protocols and seek team lead’s review
- Perform laboratory experiments and document them thoroughly
- Forecast material requirements for assigned projects
- Conduct lab maintenance and inventory management
- Analyze and present research data within the department
- Execute and guide fellow executives in downstream process development
- Collaborate with team members to decide action plans
- Provide regular updates to project leaders and monitor project progress against timelines
Educational Qualification
Master’s degree in Biotechnology.
Technical/Functional Skills
- Knowledge of downstream unit operations for large molecules
- Experience with mammalian cell culture derived mAb and/or non-mAb proteins
- Ability to interpret analytical and process data
- Familiarity with downstream process scale-up principles
- Understanding of Quality by Design (QbD) principles
- Proficiency in handling chromatographic systems
- Excellent written and oral communication skills
- Strong documentation skills (report preparation, SOPs, etc.)
- Knowledge of tangential flow filtration and data interpretation
- Proficiency in MS Excel
Experience
5-9 years of experience in downstream process development.
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