Summer Internship (SSR) Scheme of DST-SERB at CUH, Applications Invited From Biological Sciences Candidates

Summer Internship (SSR) Scheme of DST-SERB at CUH, Applications Invited From Biological Sciences Candidates

Summer Internship (SSR) Scheme of DST-SERB at CUH, Applications Invited From Biological Sciences Candidates. Central University of Haryana Summer Internship 2023. Interested and eligible applicants can check out all of the details below

The five possible interview questions that could be asked in the technical round, along with their sample answers are posted below

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Department of Biochemistry 

Central University of Haryana, Mahendergarh-12309

Advertisement for a Summer Internship under Scientific Social Responsibility (SSR) scheme of DST-SERB

Applications are invited from motivated and eligible candidates for the Summer Internship in the Dept. of Biochemistry, Central University of Haryana, Mahendergarh, Haryana. this position is advertised under the SSR scheme of DST-SERB EMEQ for its funded project.

Name of the Post/ Program: Summer Internship

No. of Posts: 01 (One)

Name of the Project: Exploration of exosome secretion inhibition against the growth and development of Plasmodium Falciparum.

Name of the PI: Dr. Mulaka Maruthi

Duration:

How to Apply: Interested candidates can apply by sending an updated CV (in the enclosed format) along with a research proposal (up to 500 words) to the principal

The last date of application: 15/06/2023.

Selection Criteria: Students selection is based on their academic profile and research proposal.

Selected candidates will be intimated by email only regarding their selection.

For further details, kindly contact: Dr Mulaka Maruthi, Email: [email protected].

Fellowship: INR 5000/- per month (consolidated)

Eligibility: Pursuing MSc or Integrated BSc-MSc (in their 4th year) in Biological Sciences.

Download the Application Format Below

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Here are five possible interview questions that could be asked in the technical round, along with their sample answers:

1. Can you briefly explain your understanding of exosome secretion and its potential role in inhibiting the growth and development of Plasmodium Falciparum? Sample Answer: Exosomes are small vesicles secreted by cells that play a role in intercellular communication. In the context of Plasmodium Falciparum, the exosome secretion process is being explored as a potential mechanism to inhibit its growth and development. By understanding the molecular interactions between exosomes and Plasmodium Falciparum, we can identify targets for therapeutic interventions to combat malaria.
2. What research experience or projects have you undertaken that are relevant to the exploration of exosome secretion inhibition and its application to combatting Plasmodium Falciparum? Sample Answer: During my undergraduate studies, I participated in a research project focused on studying the role of exosome-mediated communication in cancer cells. I investigated the cargo content of exosomes secreted by cancer cells and their impact on the tumor microenvironment. This experience provided me with a solid foundation in understanding exosome biology and its potential applications in disease-related research.
3. Describe the techniques or methodologies you would employ to study exosome secretion inhibition in the context of Plasmodium Falciparum. Sample Answer: To study exosome secretion inhibition, I would first employ various cell culture techniques to culture Plasmodium Falciparum-infected cells. Then, I would utilize techniques such as differential ultracentrifugation or size-exclusion chromatography to isolate exosomes from the cell culture supernatant. Next, I would analyze the exosomes using techniques like nanoparticle tracking analysis or electron microscopy to assess their quantity and morphology. Additionally, I would employ molecular techniques like Western blotting or mass spectrometry to analyze the cargo of exosomes and identify potential inhibitory factors.
4. What challenges do you anticipate in exploring exosome secretion inhibition against Plasmodium Falciparum, and how would you address them? Sample Answer: One challenge could be optimizing the conditions for exosome isolation and characterization from Plasmodium Falciparum-infected cells, as the presence of other cellular debris might interfere with the analysis. To address this, I would employ rigorous purification techniques and utilize appropriate controls during the isolation process. Another challenge could be identifying specific exosomal components or pathways involved in inhibiting the growth and development of Plasmodium Falciparum. I would address this by employing comprehensive proteomic or genetic approaches to identify potential targets and validate their role through functional assays.
5. In your opinion, what are the potential implications or applications of exosome secretion inhibition in combatting Plasmodium Falciparum beyond this research project? Sample Answer: The implications of exosome secretion inhibition in combatting Plasmodium Falciparum extend beyond this specific research project. Successful identification of inhibitory factors or mechanisms could lead to the development of novel therapeutic strategies against malaria. Additionally, understanding exosome-mediated intercellular communication in the context of Plasmodium Falciparum could provide insights into the parasite’s interactions with host cells, potentially leading to the discovery of new drug targets or diagnostic markers.

Remember to tailor your answers to your own research experiences and knowledge, as these sample answers are for reference purposes. Good luck with your interview!

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