Papyrus Diagnostics Enzyme Specialist Recruitment, Apply Via LinkedIn

Papyrus Diagnostics Enzyme Specialist Recruitment, Apply Via LinkedIn

Papyrus Diagnostics Enzyme Specialist Recruitment, Apply Via LinkedIn. Papyrus Diagnostics jobs. Molecular Biology and Biochemistry job opening at Papyrus Diagnostics. Interested and eligible applicants can check out all of the details on the same below

Hey there, interested to apply for this enzyme specialist role at Papyrus Diagnostics? Then check out the possible interview questions and the answers below

Job Title: Enzyme Specialist – Be a Game Changer at Papyrus Diagnostics

Last date: 16 May 2023

Description:

Papyrus Diagnostics, a cutting-edge healthcare startup spun off from the prestigious Indian Institute of Science, Bangalore, is seeking a talented and passionate Enzyme Specialist with a Ph.D., post-doctoral experience, or equivalent industry experience. As a multiple national award-winning startup, we’re revolutionizing the diagnostics landscape by developing assays for Antimicrobial Resistance (AMR) to save countless lives. If you’re a hands-on problem solver with expertise in enzyme expression, purification, and characterization using bacterial systems, as well as experience in assay development and optimization, we want you on our trailblazing team!

What you’ll be doing:

• Enzyme Expression, Purification, and Characterization
• Design, develop, and improve genotypic diagnostic assays on the Papyrus MutaCheck Platform for global priority pathogens
• Design and execute experiments in enzyme expression, purification, and characterization using bacterial systems
• Develop and optimize enzyme purification protocols using a variety of chromatography techniques
• Employ a variety of analytical techniques for enzyme characterization, such as SDS-PAGE, Western blot, and mass spectrometry
• Perform site-directed mutagenesis for enzyme engineering and assay development projects

Collaboration and Leadership

Collaborating with cross-functional teams and external partners on projects involving assay development and optimisation, enzyme expression, and purification
Leading a team of biotechnologists, working independently, and driving projects to completion.

What you’ll bring to the table:

• PhD, post-doctoral experience, or equivalent industry experience in molecular biology, biochemistry, or a related field.
• 4+ years of hands-on experience in enzyme expression, purification, and characterization using bacterial systems.
• Demonstrated expertise in techniques like ÄKTA systems, affinity chromatography (e.g., Ni-NTA), site-directed mutagenesis, and assay validation.
• Sharp analytical skills and the ability to troubleshoot complex experiments.
• Excellent communication, collaboration, and problem-solving skills.
• Adept at working under tight deadlines and effectively prioritizing tasks.
• A resourceful mindset, capable of finding innovative solutions and adapting to a bootstrapping startup environment.
• Ability to lead and motivate team members

Why join Papyrus Diagnostics:

• Contribute to groundbreaking & meaningful research that has the potential to transform lives and save millions.
• Collaborate with a team of experts from diverse backgrounds and experiences.
• Thrive in a fun, candid, and professional startup environment.
• Lead a team of biotechnologists and be recognized for your individual contributions.
• Participate in startup networking events and gain exposure to the entrepreneurial ecosystem.
• See the real-world impact of your work as you develop cutting-edge diagnostic assays for complex infectious diseases rather than just another publication

Ready to make a difference?

If your background aligns with our needs, we’ll invite you to complete a questionnaire to further explore your skills and experience. The final stage will be an online interview with the founders of Papyrus Diagnostics.

At Papyrus Diagnostics, we celebrate diversity and are committed to creating an inclusive environment for all employees. We’re excited to learn more about your unique strengths and how they can contribute to our mission to revolutionize diagnostics and save lives!

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Hey there, interested to apply for this enzyme specialist role at Papyrus Diagnostics? Then check out the possible interview questions and the answers below

1. Can you describe your experience and expertise in enzyme expression, purification, and characterization using bacterial systems? How have you applied this knowledge in previous projects or research? Answer: During my Ph.D. and subsequent industry experience, I have worked extensively on enzyme expression, purification, and characterization using bacterial systems. I have successfully expressed and purified enzymes of interest, utilizing techniques such as ÄKTA systems and affinity chromatography. I have also characterized enzymes using analytical techniques like SDS-PAGE, Western blot, and mass spectrometry.
2. How have you contributed to the development and optimization of genotypic diagnostic assays for global priority pathogens? Can you provide examples of projects you have worked on? Answer: In my previous role, I actively contributed to the design and development of genotypic diagnostic assays for global priority pathogens on the Papyrus MutaCheck Platform. I collaborated with cross-functional teams and external partners to optimize assay performance, ensuring accurate and reliable results. For instance, I played a key role in optimizing the enzyme purification protocols and validating the assays through rigorous testing and analysis.
3. Describe your experience with site-directed mutagenesis for enzyme engineering and assay development. How have you utilized this technique to enhance enzyme functionality or create novel assays? Answer: I have extensive experience in site-directed mutagenesis for enzyme engineering and assay development. In one project, I introduced specific mutations in the enzyme’s active site to enhance its catalytic efficiency. This led to the development of a more sensitive and specific diagnostic assay. I have also utilized site-directed mutagenesis to create variant enzymes for exploring new applications and improving assay performance.
4. How do you approach troubleshooting complex experiments in enzyme expression and purification? Can you share an example of a challenging situation you encountered and how you resolved it? Answer: Troubleshooting complex experiments requires a systematic approach and attention to detail. In a recent project, we faced difficulties in achieving high yields during enzyme expression. Through careful analysis and optimization of culture conditions, we identified the issue and successfully improved expression levels. I believe in thoroughly investigating each step, collaborating with colleagues, and considering alternative strategies to overcome challenges effectively.
5. How do you ensure effective communication and collaboration within cross-functional teams and while leading a team of biotechnologists? Provide examples of your experience in this area. Answer: Communication and collaboration are vital in a team-based scientific environment. I prioritize regular team meetings to ensure everyone is aligned with project goals and tasks. Additionally, I maintain open and transparent communication channels, fostering an environment where ideas and feedback are encouraged. In a recent project, I successfully led a team of biotechnologists, ensuring effective coordination and motivation to accomplish project milestones.

Remember, these questions are just samples, and it’s important to tailor them to the candidate’s specific experiences and the requirements of the job.

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